Ray Romano

Manfred 'Manny' (voice)

John Leguizamo

Sid (voice)

Denis Leary

Diego (voice)

Goran Višnjić

Soto (voice)

Jack Black

Zeke (voice)

Cedric the Entertainer

Rhino (voice)

Stephen Root

Rhino / Start (voice)

Diedrich Bader

Saber-Toothed Tiger (voice)

Alan Tudyk

Saber-Toothed Tiger / Freaky Mammal (voice)

Lorri Bagley

Female Sloth (voice)

Jane Krakowski

Female Sloth (voice)

Peter Ackerman

Dodo / Freaky Mammal (voice)